Locomotive engineer Edmund Lowe falls head-over-heels in love with musical-comedy dancer Mae Clarke. When he finds out that Clarke was mixed up in a notorious scandal, Lowe, who's no paragon of virtue himself, walks out on her. He's so upset by this turn of events that he accidentally causes a train wreck, whereupon he loses his job and becomes a hobo. Given a new lease on life in the Coast Guard, Lowe is "on call" when he spots a drowning girl off the port bow. Upon rescuing the girl, he discovers that it's Clarke, and all is forgiven. Men on Call was released minus screenwriter's credit, which is just as well.